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Child Neurol > Volume 26(4); 2018 > Article
Journal of the Korean Child Neurology Society 2018;26(4):246-250.
DOI: https://doi.org/10.26815/jkcns.2018.26.4.246    Published online December 31, 2018.
Characteristics of Meningitis with or without Enterovirus
Won Je Cho, Ye Rim Kwon, Byung Ho Cha
Department of Pediatrics, Yonsei Wonju Seve­ rance Christian Hospital, Wonju, Korea
Correspondence:  Byung Ho Cha, Tel: +82-33-741-0114, Fax: +82-33-741-0114, 
Email: cha12bho@yonsei.ac.kr
Received: 17 September 2018   • Revised: 10 October 2018   • Accepted: 10 October 2018
Abstract
Purpose
Meningitis is an acute childhood infection caused by viral or bacterial infection. The purpose of the present study is to analyze the differences between enteroviral meningitis and non-enteroviral aseptic meningitis.
Methods
From January 2013 to December 2016, we retrospectively reviewed the medical records of a total of 303 aseptic meningitis patients who visited Wonju Severance Christian Hospital. We examined demographics of all patients and analyzed serologic and cerebrospinal fluid tests, clinical symptoms, and outcomes.
Results
Of a total of 303 patients, 197(65.0%) were male, and the most cases occurred from June to November (91.8%). The most common pathogen of meningitis was found to be enterovirus (65.0%). According to the etiology, the enteroviral meningitis group had significantly more headache and enteric symptoms (P=0.0003 and P =0.0013, respectively). Furthermore, the non-enteroviral meningitis group showed pleocytosis in the cerebrospinal fluid and a significantly higher rate of seizure at 1 to 4years(P=0.0360 and P=0.0002, respectively).
Conclusion
In this study, enteroviral meningitis was the most common and the prognosis was good. When compared between two groups, neurological symptoms were frequent in patients with non-enteroviral meningitis in groups 1 to 4 years.
Key Words: Aseptic meningitis, Children, Enterovirus


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